Betty White

Earned an Emmy nomination for her guest starring role on NBC's "My Name is Earl" as the Crazy Witch Lady

Joined Sandra Bullock and Ryan Reynolds for the comedy "The Proposal"

Played herself as the victim of Wilhelmina Slater's (played by Vanessa Williams) temper in an episode of "Ugly Betty" (ABC)

Starred in a parody of "Ugly Betty," titled "Ugly Betty White" for the TV Land Awards

Joined the CBS soap opera "The Bold and the Beautiful" as Ann Douglas, the mother of arch Stephanie Forrester (played by Susan Flannery)

Again portrayed Catherine Piper in a recurring role on "Boston Legal" (ABC)

Appeared in three episodes of "The Practice" (ABC) as Carol Piper, a resident of Alan Shore's (James Spader) hometown; received an Emmy nomination for Outstanding Guest Actress

Joined Steve Martin for the comedy "Bringing Down the House"

Had a recurring role on "That '70s Show" (FOX) as Kitty's mother

Received an Emmy nomination for her guest starring role in "Yes, Dear" (CBS)

Voiced Grandma Sophie in "The Wild Thornberry's: The Origin of Donnie"

Had a regular role on the CBS sitcom "Ladies Man"

Provided some comic relief as a foul-mouthed widow in the thriller "Lake Placid"

Cast as Mrs. Wilson in the straight to video release "Dennis the Menace Strikes Again"

Played herself on a memorable episode of "The John Larroquette Show" (NBC)

Received an Emmy nomination for appearance on "Suddenly Susan" (NBC)

Played Marie Osmond's mother on the short-lived ABC sitcom "Maybe This Time"

Joined the cast of "Bob" (CBS) as Bob Newhart's boss

Reprised role of Rose Nylund for the spin-off "The Golden Palace" (CBS)

Played the memorable role of ditzy Rose Nylund on the NBC sitcom "The Golden Girls"

Had a recurring role as the snobbish Ellen, the title character's oldest daughter, on "Mama's Family" (NBC)

Hosted the NBC game show "Just Men!"

Starred in her own short-lived sitcom "The Betty White Show" (CBS)

Played Sue Ann Nivens on CBS' "The Mary Tyler Moore Show"

Hosted the syndicated animal series "The Pet Set"

Made TV-movie debut in "Vanished" (FOX)

Co-hosted the "78th Annual Tournament of Roses Parade" (NBC)

Feature film debut "Advise and Consent"

Hosted her own variety program "The Betty White Show" (ABC)

Star and producer of "Date with the Angels" (ABC)

Appeared in "The Story of Virginia Lennert" episode of "The Millionaire" (CBS)

Panelist on "Make the Connection" (NBC)

Producer and star of the syndicated sitcom "Life with Elizabeth" (retitled "The Betty White Show" in 1954)

Made TV debut after several years in radio