Rosie O'Donnell

Will host a daily radio show for Sirius XM Radio in the fall

Released her second memoir Celebrity Detox

Announced as the replacement for Meredith Viera on "The View" (ABC)

Helmed the documentary film "Aboard: Rosie's Family Cruise," about R. Family Vacations, the gay cruise that was started by O'Donnell and her partner (aired on HBO)

Returned to daytime TV as co-host of "The View" (ABC); left the show in 2007 and was replaced by Whoopi Goldberg

Cast in the role of Golde, the wife of Harvey Fierstein's 'Tevye the milkman' in the Broadway revival of the musical, "Fiddler on the Roof"

Co-starred as a developmentally disabled woman opposite Andie MacDowell in the CBS movie "Riding the Bus With My Sister"; directed by Anjelica Huston

Played a lesbian on an episode of "Will & Grace" (NBC) only a month before she officially 'came out'

Published her memoir Find Me

Resigned from daytime television and returned to doing stand-up

Severed her connection with Gruner & Jahr USA Publishing and resigned from the Rosie Magazine

Assumed role of the Cat in the Hat in the Broadway musical "Seussical" while originator David Shiner was on vacation

Narrated the Oscar-nominated documentary "Artists and Orphans: A True Drama"

Became the editorial director of McCall's magazine; retitled it Rosie in 2001; ceased publication at the end of 2002

Hosted "The 42nd Annual Grammy Awards"

Supplied the voice of Terkoz for Disney's animated "Tarzan"

Portrayed a baseball-loving nun in M. Night Shyamalan's "Wide Awake"

Served as host for the annual Tony Awards telecast on CBS for two consecutive years

Had a memorable role in Ted Demme's "Beautiful Girls"

Hosted the daily syndicated talk show "The Rosie O'Donnell Show"; also served as executive producer

Made Broadway debut as Rizzo in a revival of the musical "Grease"

Offered a bright performance in Garry Marshall's "Exit to Eden" as half of a team of undercover cops

Played Betty Rubble in the live-action feature version of "The Flintstones"

Joined Richard Dreyfuss and Emilio Estevez for the sequel, "Another Stakeout"

Played Meg Ryan's best buddy in "Sleepless in Seattle"

Made feature acting debut in Penny Marshall's "A League of Their Own"

Starred in the short-lived FOX sitcom "Stand By Your Man"

Produced and hosted VH-1's half-hour series "Stand Up Spotlight"

TV series debut as Nell Carter's dental-hygenist neighbor on "Gimme a Break" (NBC)

TV debut on the syndicated series "Star Search"; winning the comedy competition five times by decade's end

Professional debut as comedian at the local Ground Round restaurant's open-mike night at age 16

Made her stage debut as Glinda, the Good Witch, in a second grade production of "The Wizard of Oz"