James Pickens Upcoming Appearances

Derek receives a surprise visit from his sister (Embeth Davidtz); Cristina scrubs in for a rare procedure, to the envy of her peers; Addison and George treat a pregnant woman with an unusual problem; and Alex ponders his future in medicine.

The men of Seattle Grace go on a camping trip together; Addison and Callie team up on a case; Meredith assists Mark Sloan with a procedure unlike any she has experienced; and Bailey confronts Cristina on her recent actions at the hospital.

George s ailing father (George Dzundza) needs heart surgery; Meredith is determined to have a more positive outlook on life as she treats an injured girl who s closer to her nanny than her working mom; Derek and Addison try to be civil to each other.

Victims of a serious traffic accident fill the ER. Meanwhile, Cristina battles guilt about hiding Burke s tremor; Izzie tests the bounds of her probation.

Burke and Cristina s relationship is strained; Meredith s half sister, Molly (Mandy Siegfried), is admitted to the hospital; and Mark and Derek must work together when two close-knit brothers seek medical help.

Part 1 of 2. After a successful heart operation, George s father (George Dzundza) undergoes cancer surgery; Thatcher Grey (Jeff Perry) visits the hospital to see his new granddaughter; and Meredith discovers that Derek isn t a sound sleeper.

Part 1 of 2. After a successful heart operation, George s father (George Dzundza) undergoes cancer surgery; Thatcher Grey (Jeff Perry) visits the hospital to see his new granddaughter; and Meredith discovers that Derek isn t a sound sleeper.

Nana Mary (Shelley Winters) amuses Roseanne and Jackie with a box of their childhood treasures; Bev regales Becky and Darlene with colorful stories about their mother; and Dan and his pals play poker with Leon and Scott.

Dan weighs the options of giving up his boring garage job for a construction project with his pals (James Pickens Jr., John McConnell). Meanwhile, Jackie (Laurie Metcalf) surfs the Internet---and becomes addicted.

Rumors of the chief s retirement spread around the hospital; Bailey proposes the creation of a free clinic; and other Seattle Grace doctors receive proposals of a different sort.

As Cristina weighs her marriage proposal, Ellis (Kate Burton) experiences a change in her medical condition; and a surgical patient endangers the lives of her surgeons when her blood becomes toxic. Meanwhile, the Denny Duquette Memorial Clinic opens.

The beginning of a three-part story arc in which a ferryboat disaster poses stern challenges to the interns. Meanwhile, Cristina has trouble telling Meredith that she and Burke are engaged; and Sydney (Kali Rocha) decides she wants to be chief resident.

Meredith remains missing after falling into the water at the site of the ferry disaster, where Izzie must perform delicate brain surgery on the fly while taking instructions from the chief over the phone.

As Bailey, Burke, Addison and the chief work feverishly to save her life, Meredith receives affirmation from an unexpected source. But Cristina can t cope with the prospect of her “person” not pulling through.

The race for chief heats up as a new competitor enters the race; tensions mount between Izzie and George; Callie must reveal a big secret; Derek treats a patient close to him; and Alex continues his work with Jane Doe (Elizabeth Reaser).

George comforts Izzie as she faces her painful past; Derek questions his relationship with Meredith while she must decide what sort of relationship she ll have with her stepmother (Mare Winningham).

While the interns cram for an exam, the attendings jockeying to succeed Webber as chief offer the very best of care to a very important patient: the hospital s board chair. Meanwhile, Burke plans his wedding without much help from Cristina.

Dan returns home to rumors about his behavior; while Roseanne helps Jackie move. Fisher: Matt Roth. Crystal: Natalie West. Chuck: James Pickens Jr. Anne Marie: Adilah Barnes. Jackie: Laurie Metcalf.