Michelle Pfeiffer

Re-teamed with director Stephen Frears for "Cheri"

Cast as Velma Von Tussel in the remake of the John Water's film "Hairspray"

Played the evil witch Laima in the fairy tale "Stardust," a feature based on the fantasy adventure novel by Neil Gaiman

Received a star on the Hollywood Walk of Fame (August)

Portrayed a woman who murder's her boyfriend and has her daughter taken away in "White Oleander"; earned a SAG nomination for Best Supporting Actress

Portrayed a lawyer fighting to help an autistic father (Sean Penn) retain custody of his daughter in "I Am Sam"

Co-starred with Harrison Ford in the Robert Zemeckis's thriller "What Lies Beneath"

Co-starred as Tatiana in a film version of "A Mid Summer Night's Dream"

Produced and starred in "The Deep End of the Ocean"

Provided a character voice for the DreamWorks animated film "The Prince of Egypt"

Co-starred with Jessica Lange in "A Thousand Acres"; a modern-day version of "King Lear" adapted from Jane Smiley's Pulitzer Prize-winning novel

Debut as executive producer (also acted), "One Fine Day"; also starred George Clooney

Teamed with Robert Redford as a rising TV newsreporter in "Up Close and Personal"

Took supporting role of the ghost of Peter Gallagher's wife in "To Gillian on Her 37th Birthday"; film written by David E. Kelley

Had box-office hit as former Marine-turned-teacher LouAnne Johnson in "Dangerous Minds"

Made uncredited cameo appearance in an episode of "Picket Fences"; created by husband David E. Kelley

Reteamed with Jack Nicholson for "Wolf"

Received second Best Actress Oscar nomination as a woman traveling to the funeral of President John F Kennedy in "Love Field"

Won raves for her performance as Catwoman/Selina Kyle in "Batman Returns"; Tim Burton directed

Downplayed her looks to portray a working-class waitress romanced by a short-order cook (Al Pacino) in "Frankie & Johnny"

With producing partner Kate Guinzberg, formed first look deal with Orion Pictures

Earned Best Actress Oscar nomination as the chanteuse Susie Diamond in "The Fabulous Baker Boys"

Made NYC stage acting debut in "Twelfth Night"; performed in Central Park under the auspices of Joseph Papp's New York Shakespeare Festival

Played a widowed Mafia wife in Jonathan Demme's comedy "Married to the Mob"

Received a Best Supporting Actress Oscar nomination as the married Madame de Tourval in Stephen Frears' "Dangerous Liaisons"

First box-office hit, "The Witches of Eastwick"; co-starred with Jack Nicholson, Susan Sarandon and Cher

Played title role in "Natica Jackson," an episode in the the three-part PBS series "Tales From the Hollywood Hills"; last major television acting role to date

Directed by her then-husband Peter Horton in the ABC TV-movie "One Too Many"

Earned critical notice, co-starring with Al Pacino in Brian De Palma's gangster classic "Scarface"

Landed female lead in the film sequel "Grease 2"

Feature film debut, "The Hollywood Knights"

Was a regular on the Aaron Spelling-produced series "B.A.D. Cats" (ABC)

TV debut as regular on the short-lived ABC sitcom "Delta House" which was inspired by the feature film "Animal House"

TV movie debut in "The Solitary Man" (CBS)

Raised in Orange County, CA

Reportedly turned down the lead role of "Evita" in the film because she did not want to work on location

TV acting debut in bit role on ABC's "Fantasy Island"

Won title of Miss Orange County