Is It the End for Grey's Anatomy's Owen and Cristina?

Uh oh! It looks like bad news for fans who hope that Grey's Anatomy docs Owen Hunt (Kevin McKidd) and Cristina Yang (Sandra Oh) can still save their marriage.

"It's just sad and hard right now," Oh told TV Guide Magazine at Sunday's L.A. benefit for Mariska Hargitay's Joyful Heart Foundation which supports survivors of sexual assault, domestic violence and child abuse. "If there's [hope], I can't see it right now."

In the episode that aired Feb. 23, Cristina started to suspect that Owen was having an affair, and those suspicions will continue in the March 15 episode, "One Step Too Far."

"What I really am happy with, is that a dissolution of a relationship — if it is a dissolution — takes a long time and is painful. We're spending time with them, seeing it happen," says Oh. "And not quickly, but painfully, day by day."

"It's real, it's messy and it's also why we root for them so much," adds costar Kim Raver. Though Raver's character, Teddy, has currently written off her friendship with Owen, there seems to be a glimmer of hope that the former best friends may reconcile. "In terms of Teddy and Owen, the rift is so dramatic that maybe that walk back home hopefully will be an interesting journey," Raver says. "That's what's interesting to me about the relationship now."

Oh also says that the subject of sexual assault will come up in an future episode, and the entire cast will be involved. "We're dealing with a very dramatic side of this issue," she says. "I really admire Mariska and her work, not only on her show and the influence and the impact that she has on the show for this work, but it translates also in our work on Grey's Anatomy."

"It touches all of us, even if we don't know that it does," adds Raver. "I think the fact that we're discussing it is the first step to aiding it."

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