Don and his team search for a 30-year-old teacher and her teenage boyfriend, who are on a violent cross-country crime spree; Charlie and Amita share an intimate moment.
Don and his team desperately search for Megan, who was kidnapped and taken hostage by a disturbed woman on a violent crime spree.
When a multimillion-dollar painting is stolen from a museum, Don and his team believe it is part of an insurance scam.
An interpreter in the Chinese consulate is killed in a hit and run, but Charlie figures out that it wasn't an accident and the investigation leads Don to believe there's a leak in the Department of Justice.
After a father is gunned down on the freeway, Don and his team must determine if it was a random act or the work of a serial killer.
Don and his team investigate a murder at a horse track; as Charlie digs deeper into the victim s life he discovers an elaborate gambling scheme and a connection to a third party, sending the case in a new direction.
When a series of blackouts puts Los Angeles in the dark, Don and his team must determine if it is terrorist activity; sparks begin to fly between Don and his former trainee, Special Agent Warner.
Don and his team investigate a minor-league baseball player's death; a fantasy-league player's statistical analysis that identifies which players use steroids leads the FBI to a possible motive and potential killer.
Don, Charlie and the team look into problems with toxic waste disposal when several children are hurt after a sinkhole collapses underneath a school playground.
While investigating the death of a Senator, Don's team discovers that someone is using a behavior modification program, that was discontinued, to get the participants to commit murder. Meanwhile, Larry announces that he is leaving to go to space for six months.
A serial killer starts stalking Internet sexual predators and murdering them to stop them from hurting young girls. The team tracks the killer and discovers that it's the wife of one of the murder victims. Meanwhile, as Larry prepares for his NASA mission, he gets a call telling him he's not going to be able to go after all. Charlie makes a call and vouches for him, and NASA decides to let him go. They family has a send-o…more
A man finds a teenage girl nearly beaten to death. Don and the team are called in to investigate and discover that the girl escaped from a polygamous cult headed by a leader who is running from the FBI. Charlie and Amita decipher a breeding chart found at the leader's last known location and then track him to his current location. Meanwhile, Alan has dinner with Mildred.
Conflicting government agencies look for the wreckage of an expensive yacht that sank during a race.
When two police officers are murdered during a robbery that is part of a string of robberies at upscale restaurants, Don's team is called in. Charlie helps Don to figure out where the money is being laundered. Meanwhile, Don is required to go see a psychologist and Charlie helps Millie with fundraising for the University.
A badge of a missing LAPD officer is found causing Don and the FBI to re-open the case. The police suspect a former gang member turned activist is responsible, but Charlie analyzes the data and figures out where the police officer was killed leading the FBI to a whole new pool of suspects. Meanwhile, Don and Liz's relationship progresses.
A mixed-martial arts fighter dies training for a championship match. The man who was practicing with him, Ben, turns out to be an old friend of David, so the team is brought into the case. Ben is the number one suspect when the police learn that the same thing happened to another one of his sparring partners. They learn that the boxer was poisoned and find evidence pointing to Ben. The team looks for evidence to clear him…more
Don goes to his therapy session and is forced to turn off his cell phone and stay out of contact with his team. Megan must head up the search for a kidnapped boy in Don's absence. Charlie and Amita try to help Megan track down the kidnapper. Meanwhile, Don realizes that he has some control issues.
When an old colleague comes to Charlie with a conspiracy theory and then winds up dead the next day, Charlie calls on Don to investigate. The team connects her death as well as four others to a voter fraud conspiracy. Meanwhile, Megan is asked to take another assignment.
After a small plane crashes, Charlie tests its flight computer to uncover what brought it down.
Don and Charlie disagree over who is the real serial letter bomber. In the end, they must call on their lead suspect to help them track down the real bomber and disarm one of his bombs. Meanwhile, Millie and Alan make a bet about who can go longer without buying something they don't really need.
Don believes that a death row inmate has an ulterior motive when he suddenly wants to confess the whereabouts of bodies he buried during his days as a hit man for the mob.
Don and the FBI uncover a possible terrorist attack on Los Angeles that targets the city's water supply. Charlie has a difficult time working with a terrorist specialist brought in to work on the case and it turns out that the specialist had something to do with the terrorist attack. Meanwhile, Alan tries to help with the case, but Don doesn't want him working on the cases.
When thieves hijack a truck filled with valuable medical supplies, $50 million dollars intended for a relief effort in Zambia, and two aid workers, the FBI races a second violent crew intent on getting to the goods first. Meanwhile, Don asks Charlie to come to a therapy session with him and they begin repairing their relationship. Don also announces to the team that he is in a relationship with Liz.
Thieves hijack a truck full of medical supplies, $50 million intended for a Zambian relief effort, and two aid workers.
After a brilliant bomber tries to give Charlie a message about a "Janus List" of secret service double agents, the team must find the list as well as the bomber's murderer. Megan returns to the team, just in time to learn that their very own agent, Colby, is a spy.