| Appeared in stage productions in NYC |
| Shot a few commercials in NYC, including one for Amstel Light |
1992 | Co-founded Harlem's Dream Yard Drama Project, a nonprofit arts and education program for urban kids |
1995 | Made TV-movie debut in "The Commish: In the Shadow of the Gallows" |
1995 | TV debut as a guest on the Fox comedy "Misery Loves Company" |
1996 | Co-starred with Scott Bakula on the short-lived CBS series "Mr. & Mrs. Smith" |
1997 | Landed recurring role of Dr. Anna Del Amico on NBC medical drama "ER"; made regular for the 1997-98 season |
1998 | Played leading role opposite Ben Stiller in "Permanent Midnight" |
1999 | Co-starred with Mel Gibson in Brian Helgeland's "Payback" |
2000 | Cast as a sexy waitress who enjoys karaoke in "Duets" |
2000 | Portrayed the bar owner in "Coyote Ugly" |
2001 | Cast in the dark comedy "100 Mile Rule" |
2001 | Starred in the IMAX movie "China: The Panda Adventure" |
2002 | Cast as Bob Crane's second wife Patricia in director Paul Schrader's "Auto Focus" |
2003 | Played a Las Vegas casino waitress who falls for William H. Macy in "The Cooler"; earned Golden Globe and SAG nominations for Supporting Actress |
2004 | Cast in John Sayles' political satire "Silver City" |
2004 | Cast opposite Johnny Depp in "The Secret Window" |
2005 | Co-starred with Viggo Mortensen in David Cronenberg's "A History of Violence"; earned a Golden Globe nomination for Lead Actress |
2005 | Starred with Ethan Hawke and Laurence Fishburne in "Assault on Precinct 13" |
2006 | Joined Aaron Eckhart in the ensemble cast of "Thank You for Smoking"; the directorial debut of Jason Reitman |
2006 | Played the wife of a rescued Port Authority officer in Oliver Stone's "World Trade Center" |
2007 | Cast in "The Jane Austen Book Club," as Jocelyn an independent, 50-something dog-breeder and organizer of the Club |
2008 | Cast in the fantasy action film "The Mummy: Tomb of the Dragon Emperor" |
2009 | Played Robin Wright Penn's bipolar mother in "The Private Lives of Pippa Lee," written and directed by Rebecca Miller |
2009 | Starred in the indie drama "Downloading Nancy"; earned an Independent Spirit Award nomination for Best Female Lead |
2010 | Appeared in the ensemble comedy "Grown Ups," about five friends who reunite for a Fourth of July holiday weekend; film starred Adam Sandler, Kevin James, Chris Rock, David Spade, and Rob Schneider |
2010 | Cast alongside Ben Affleck in the recession drama "The Company Men"; directed by John Wells |
2011 | Cast as brilliant but abrasive homicide detective Jane Timoney (played by Helen Mirren on the original British production) on NBC's adaptation of "Prime Suspect" |
