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'Gossip Girl': Best and Worst Moments From the Series

Six seasons. Countless hookups and breakups. Hundreds of trendsetting outfits. Dozens of schemes. Multiple love interests. Several long-lost family members. And unending snark from the all-seeing Gossip Girl ... until now. As "Gossip Girl" signs off for the final time and the show's teens graduate and move on to adulthood, we take a look back at the series' most memorable moments. — Kelly Woo, Yahoo! TV

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Photo By The CW Fri, Dec 14, 2012 2:00 PM PST

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GOSSIP GIRL'S BEST LINE:
"They say blood is thicker than water. But it's also a lot harder to clean up when it spills." (Season 5, Episode 2)

Gossip Girl doesn't spare the snark for anyone. More of her best quips: "S's new boy's name is -- oh, who cares?" (Season 1, Episode 2); "Sound the trumpet, strumpets" (Season 2, Episode 4); and "Sticks and stones may break bones, but a poison pen is the best revenge" (Season 2, Episode 16).
GOSSIP GIRL'S BEST LINE:
"They say blood is thicker than water. But it's also a lot harder to clean up when it spills." (Season 5, Episode 2)

Gossip Girl doesn't spare the snark for anyone. More of her best quips: "S's new boy's name is -- oh, who cares?" (Season 1, Episode 2); "Sound the trumpet, strumpets" (Season 2, Episode 4); and "Sticks and stones may break bones, but a poison pen is the best revenge" (Season 2, Episode 16).

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