Dean and Sam watch as the Devil emerges from Hell. The brothers and Bobby deal with the aftermath of Lucifer rising and the stunning news from Chuck the Prophet that Castiel was blown to bits by the archangels.
Castiel tells Sam and Dean that he is going to search for God, who will be able to defeat Lucifer. Bobby's old hunter friend, Rufus, panics about demons attacking his town, and begs Bobby for help. Sam and Dean arrive at the town and realize there is a spell over the townspeople, making them hallucinate that they are demons and causing them to kill one another.
Not sure he trusts himself anymore, Sam decides to give up hunting, but a late-night visitor will not let him off the hook that easily. Dean, intent on stopping the Apocalypse, continues hunting on his own and teams up with Castiel to find the Archangel Raphael, as Castiel believes Raphael knows God's location.
Sam tells Dean he wants to rejoin Dean in the battle of the Apocalypse, but Dean tells Sam that they are better off apart. Later, Dean awakens five years in the future in an abandoned city where he is attacked by humans infected with a demonic virus that turns humans into Zombies. Zachariah appears to Dean and explains about the world that exists because of Dean saying no to help the angels fight Lucifer. Dean meets up wi…more
Sam and Dean decide to start hunting together again and their first case leads them to a small town whose inhabitants are being killed by famous dead icons like Abraham Lincoln and James Dean's car. However, after two teenage girls come forward and claim Paris Hilton kidnapped their friend, the brothers are not sure what they are hunting anymore.
Sam and Dean investigate a series of odd murders that strangely resemble fairytales and urban legends. The brother’s track down an 11-year-old boy named Jesse and realize that whatever Jesse believes is coming true. Castiel tells Sam and Dean that Jesse is a serious threat and needs to be eliminated.
Sam and Dean discover a witch is running a high-stakes poker game where the currency is life years vs. money. Bobby sees the game as a chance to get out of the wheelchair and bets 25 years, but loses. As Bobby begins to age rapidly, Dean steps in to save him but also ends up turning into an old man, leaving Sam holding the bag for their survival.
The Trickster throws Sam and Dean into an alternate universe where they are characters in different television series, including a sexy medical show, a Japanese game show, a forensics show and a sitcom. The brothers realize the only way to get out of this world is to play along and become the characters in the shows. However, Castiel appears and warns them this universe is dangerous and they must get out before they becom…more
Super fan Becky uses Chuck's phone to trick Sam and Dean into attending a Supernatural fan convention, complete with fans dressed up as Sam and Dean. One of the activities is a live action role-playing game, but things quickly turn sour after a real ghost appears on the scene.
Sam, Dean and Castiel track down the Colt and head off to find Lucifer to send him back to Hell. It is a hunters' reunion when the crew joins forces with Bobby, Ellen and Jo for what could be their last night on Earth.
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