Christopher screens Cleaver for cast and crew (and investors), and the whole gang attends. Tony (and everyone else) notices that the mob boss in the movie (played by Daniel Baldwin) bears a striking resemblance to Tony, right down to his affair with the protagonist's fiancée. Carmela gets pissed off at the intimation that Tony had an affair with Adriana. Carm confronts Christopher about the movie, and Christopher tells her she's crazy, insists that Tony didn't sleep with Adriana, and reminds Carmela that Adriana left Christopher for another man. Christopher convinces Tim "J.T." Daly (via a clunk to the side of the head with a Humanitas Award) to pretend he came up with the whole boss/fiancée subplot. J.T. finds Tony and claims that he based the plot on an old movie, not on any real-life events. Tony talks to Melfi about his feelings of betrayal and hurt over the fact that he treated Christopher like a son, and Christopher seems to hate him. The episode ends in Godfather-like fashion, with Carmela and Tony serving as godparents to Christopher and Kelly's baby, even though Tony and Christopher are clearly still wary with one another.
At the after-party, Tony tries to find out from Phil who the next New York boss will be. Phil sort of endorses Gerry the Hairdo, but Tony hears that Doc Santoro (the one from last week whom no one likes) is next in line. Gerry gets whacked by one of Doc Santoro's goons while eating dinner with Silvio. Tony talks to Little Carmine about the lack of leadership and tries to convince Little Carmine to go for boss. Little Carmine isn't interested and relates that his wife actually convinced him to quit the Family business, and now he's happy. Phil Leotardo celebrates his late brother's birthday and gets pissed off over his whacking all over again, as well as over the many recent deaths in the New York family. Phil decides there can't be any more deaths.
Johnny Sack is suffering from lung cancer, which has spread, and his doctor gives him three months to live. An orderly, who is also an oncologist when not serving time for killing his wife and a few others who got in the way, starts advising Johnny on his treatment, and he thinks Johnny could have a lot longer to live. Johnny starts telling mob tales in prison, and also takes up smoking again. Ginny gets pissed and blames his cancer on his negative attitude. Later, Doc Orderly admits that Johnny is dying, and John dies surrounded by Ginny and his daughters. Ginny's brother informs Tony and the crew, and they raise a toast to Johnny Sack. RIP, Mr. Sacramoni.