Alex O'Loughlin stars as Dr. Andy Yablonski on "Three Rivers." CBS/John P. Filo - Friday, September, 25, 2009, 11:25 PM

The cast of "Three Rivers." CBS/George Holz - Friday, September, 25, 2009, 11:25 PM

Daniel Henney stars as Dr. David Lee on "Three Rivers." CBS/George Holz - Friday, September, 25, 2009, 11:25 PM

Katherine Moennig stars as Dr. Miranda Foster on "Three Rivers." CBS/George Holz - Friday, September, 25, 2009, 11:25 PM

Alfre Woodard stars as Dr. Sophia Jordan on "Three Rivers." CBS/Cliff Lipson - Friday, September, 25, 2009, 11:25 PM

Justina Machado stars as Pam Acosta on "Three Rivers." CBS/John P. Filo - Friday, September, 25, 2009, 11:25 PM